phospholipase d meaning in English

磷脂酶d,磷酯酶d

Spla 2 can significantly inhibits egf - induced egf receptorautophosphorylation , which also resulted in the inhibitionon egf - induced phospholipase d activation and tyrosine phosphorylation of phospholipase c - g 1 . under the same condition , spla 2 can induce intracellular ceramidegeneration . moreover , exogenous ceramide analogs can also significantly inhibit such biologicalevent induced by egf , suggesting that ceramide may play an important role in spla 2 - induced cell death and the signaling events
在相同的条件下，分泌型磷脂酶a亦能诱导细胞内神经酰胺生2成的增加；外源性的神经酰胺类似物也能有效的抑制表皮生长因子诱导的这些生物事件，提示神经酰胺在分泌型磷脂酶a所介导的细胞死亡和信号传导事件2中起着重要的作用。
Both spla 2 and ceramidehave been shown to inhibit bradykinin - , and pma - induced phospholipase d activation . these results indicated the existence of a subtle intertwined regulatory interaction between intracellular phosphoglycerol lipids and sphingolipids signaling pathways . in addition , we also found that spla can 2 down regulate theepidermal growth factor ( egf ) receptor activation
此外，我们还发现分泌型磷脂酶a能下调表皮生长因子受体的活化，它能明显的抑制表皮生长因子诱导2的受体自身磷酸化，并抑制表皮生长因子诱导的磷脂酶d活性和磷脂酶c - g的1酪氨酸磷酸化。